England suffered another blow as Westham midfielder Declan Rice withdrew from the England camp.
Declan Rice withdrew from the squad for upcoming games against Albania and San Marino, with England saying the holding midfielder has been unable to train due to illness since reporting for duty on Monday.
England will have to seal qualification for the 2022 World Cup without its first-choice midfielder.
Rice has returned to West Ham and Gareth Southgate is not expected to make further additions to his squad.
Rice has started five of England’s World Cup qualifiers, most recently playing 90 minutes of their 1-1 draw with Hungary in October.
Rice is the latest member of the England squad to drop out of this camp, following Manchester United's Marcus Rashford and Southampton's James Ward-Prowse.
Chelsea's Mason Mount and United's Luke Shaw are yet to report to St George's Park, but have not been ruled out of this month's World Cup qualifiers.
A statement from the FA read: "Having been unable to train due to illness since reporting to St George's Park, the midfielder has returned to West Ham United and will play no part in the forthcoming FIFA World Cup qualifiers.
England needs a maximum of four points from its games against Albania at home on Friday and San Marino away on Monday to finish first in their group and earn automatic qualification to next year's tournament in Qatar.